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Method for increasing the specific production rate

2023-06-21 来源:爱go旅游网
专利内容由知识产权出版社提供

专利名称:Method for increasing the specific

production rate of eukaryotic cells

发明人:Oliver Popp申请号:US15428279申请日:20170209公开号:US10336983B2公开日:20190702

摘要:The current invention reports the use of meta-tyrosine for increasing thespecific productivity of a eukaryotic cell that produces/expresses a polypeptide. In thecurrent method it is not necessary to perform a temperature-, osmolality- or pH shift orto add drugs like valproic acid or sodium butyrate to modulate the specific productivityof the cultivated cells. The method does not affect cell viability or product titer.

申请人:Hoffmann-La Roche Inc.

地址:Little Falls NJ US

国籍:US

代理人:Steven Cui

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