专利名称：METHOD TO AMPLIFY TRANSVERSE
TUNNELING CURRENT DISCRIMINATION OFDNA NUCLEOTIDES VIA NUCLEOTIDE SITESPECIFIC ATTACHMENT OF DYE-PEPTIDE
发明人：Thomas Young CHANG,Philip L. STEINER,Kim
Yang LEE,David S. KUO
申请号：US15886736申请日：20180201
公开号：US20180258480A1公开日：20180913
专利附图：
摘要：Apparatus and methods to identify nucleotides of a DNA strand. The methodincludes exposing the DNA strand to a first dye or peptide, attaching the first dye orpeptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptidechanging a conductance of the first type of nucleotide to which the first dye or peptide isattached, and measuring a tunneling current signal for all nucleotides of the DNA strand,the changed conductance of the first type of nucleotide providing amplified tunnelingcurrent discrimination of the nucleotides of the DNA strand.
申请人：SEAGATE TECHNOLOGY LLC
地址：Cupertino CA US
国籍：US
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