专利名称:DNA encoding a protein-coupled receptor
kinase
发明人:Marcy E. MacDonald,James F.
Gusella,Christine Ambrose
申请号:US07/980526申请日:19921130公开号:US05366889A公开日:19941122
摘要:This invention relates to a DNA segment which encodes at least one member ofthe family of mammalian G protein-coupled receptor kinases, which maps to theHuntington's disease region within the terminal cytogenic subband of the short arm ofchromosome 4, 4p16.3, between DNA marker D4S10 and the telomere region. Further,this invention provides the substantially purified expression product of a gene from theHuntington's disease region of the chromosome, as well as related diagnostic andtherapeutic uses.
申请人:THE GENERAL HOSPITAL CORPORATION
代理机构:Sterne, Kessler, Goldstein & Fox
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